SYNTHESIS AND PHYSICAL-CHEMICAL ANALYSIS OF THE COORDINATION COMPOUNDS OF Cu(II) BASED ON 3-ETHOXYSALICYLALDEHYDE 4-CYCLOHEXYL-THIOSEMICARBAZONE
Roman RUSNAC, Andrei CIURSIN, Sergiu ȘOVA, Angela SÎRBU, Aurelian GULEA Universitatea de Stat din Moldova
Abstract
In this article, methods of synthesis and physicochemical analysis of 5 coordination compounds based on Cu(II) ion and 3-ethoxysalicylic aldehyde 4-cyclohexyl-thiosemicarbazone are described. In the first step, the synthesis of the ligand was carried out by means of two classical methods with subsequent refinement, thus obtaining the H2L as a chelator of copper(II) ions. 1H, 13C and 15N-NMR spectroscopy, 13C-DEPT-135 NMR and 15N HSQC-NMR spectroscopy were applied to investigate the structure and geometry of the 3-ethoxysalicylic aldehyde 4-cyclohexyl-thiosemicarbazone. The synthesized substances were analyzed by means of modern research methods such as: FTIR spectroscopy, UV-vis and elemental analysis, single crystal X-ray diffraction; the biological activity is under study.
Keywords: coordination compounds, 4-cyclohexyl-thiosemicarbazone, 3-etoxysalicylic aldehyde.
