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ASPECTS OF WATER METABOLISM IN EXPERIMENTAL DIABETES ASSOCIATED WITH THE ADMINISTRATION OF THE PHYTOPREPARATION SEV-3

Iurie BACALOV, Adriana DRUȚA, Elena CHIRIȚA, Aurelia CRIVOI, Universitatea de Stat din Moldova

Authors

USM ADMIN

Abstract

Currently, increased attention is being paid to the investigation of the pathogenetic mechanisms of diabetes melli-tus and to the development of strategies aimed at ameliorating the metabolic disturbances associated with this patho-logy. Medicinal plants and phytotherapeutic preparations play an important role in this context due to their broadspectrum of biological activity and favorable safety profile. Administration of the phytopreparation SEV-3 under con-ditions of experimental diabetes contributed to the improvement of carbohydrate and water metabolism, as evidencedby a reduction in hyperglycemia, a partial increase in insulin levels, and a decrease in polydipsia and polyuria. Theobtained results demonstrated the absence of disruptive metabolic effects in healthy animals, confirming the goodtolerability of the preparation. Thus, the phytopreparation SEV-3, exerting a complex metabolic action, may be consi-dered a potential phytotherapeutic adjuvant in the correction of metabolic disturbances induced by diabetes mellitus.Keywords: alloxan-induced diabetes, phytopreparation, water, urine, glucose, insulin, complications.

DOI: https://doi.org/10.59295/sum1(191)2026_6