THE INFLUENCE OF DIETARY RATIONS ADAPTED TO THE HYPERSTHENIC CONSTITUTIONAL TYPE ON THE ACTIVITY OF PROTEOLYTIC ENZYMES IN DIFFERENT STRUCTURES OF THE GASTROINTESTINAL TRACT IN HYPOSTRESS-REACTIVE RATS

Ion MEREUȚĂ,Tudor STRUTINSCHI,Anastasia BABILEVA,Lilia POLEACOVA,Universitatea de Stat din Moldova

Abstract

The study investigates the influence of dietary rations with caloric structures adapted to the hypersthenic con- stitutional type on the activity of proteolytic enzymes in hypostress-reactive rats. Four dietary variants containing 20–30% protein were analyzed. The results show that higher protein intake leads to a moderate but consistent in- crease in protease activity in the stomach, pancreas, and small intestine mucosa. The most pronounced enzymatic response occurred in the small intestine, where proteolytic activity became statistically significant at 30% protein. Variations in pancreatic activity suggest a combined influence of diet composition and the metabolic specificities of hypostress-reactive animals. The study confirms that digestion in the hypersthenic type is less sensitive to dietary modifications, yet increased protein intake can synchronously enhance digestive protease activity. These findings highlight the importance of caloric structure in regulating enzymatic function and maintaining metabolic processes within sanogenic limits. Keywords: hypersthenic type, hypostress-reactive rats, proteases, metabolism, dietary rations, digestion, proteins, pancreas, small intestine, enzymatic activity.

DOI: https://doi.org/10.59295/sum1(191)2026_16