MECANISMUL DE PROTEOLIZĂ A FICOCIANINEI, PROTEINEI BIOACTIVE DIN SPIRULINĂ SUB ACŢIUNEA PAPAINEI

Angela RUDAKOVA, Andrei SHUTOV, Serghei RUDACOV, Valentina BULIMAGA, Natalia CLIMOVA, Irina KAHOVSKAIA, Maria PISOVA Universitatea de Stat din Moldova

Abstract

MECHANISM OF PROTEOLYSIS OF C-PHYCOCYANIN, BIOACTIVE PROTEIN FROM SPIRULINA, UNDER THE ACTION OF PAPAIN

The elaboration of the procedures of obtaining of bioactive peptides derived from phycocyanin, as a result of it proteolytic hydrolysis presents great interest for researchers in the terms of theirs use as anti-cancer drugs and for other therapeutic properties. It can be assumed that peptides derived from phycocyanin could manifest more pronounced therapeutic effects compared to phycocyanin. Dynamics of phycocyanin proteolisis by papain, as well as mechanism of phycocyanin hydrolysis were studied in the present work. Keywords: Spirulina, phycocyanin, proteolysis, bioactive peptides.