SINTEZA DIRIJATĂ A BAZELOR SCHIFF CARE CONŢIN HIDRAZINOBENZOTIAZOL, 4-AMINOTRIAZOL, LIZINĂ ŞI COMPUŞII LOR COORDINATIVI

Anastasia PAHOLNIŢCAIA Universitatea de Stat din Moldova

Abstract

DIRECTED SYNTHESIS OF SCHIFF BASES THAT CONTAIN HYDRAZINOBENZOTHIAZOLE, 4-AMINOTRIAZOLE, LYSINE AND COORDINATION COMPOUNDS WITH THESE LIGANDS

The paper presents a review of the Schiff bases that contain hydrazinobenzothiazole, 4-aminotriazole and lysine and coordination compounds with these ligands described in the literature. 3d metal coordination compounds with these ligands have different composition, structure and properties. Both ligands and coordination compounds manifest antitumor, antibacterial, and antituberculous activities. Copper(II) coordination compounds with these ligands manifest better antitumor activity than corresponding Schiff bases. Keywords: Schiff bases, complexes, copper, cobalt, nickel, biological activity.