FUNCȚIONALIZAREA RADICALICĂ A LEGĂTURILOR C-H ÎN COMPUȘII NATURALI

Vladilena GÎRBU Institutul de Chimie

Аннотация

THE RADICAL C-H FUNCTIONALIZATION OF NATURAL COMPOUNDS

Selective functionalization of complex scaffolds is a promising approach to increase the pharmacological profiles of natural products and their derivatives. Various C-H functionalizations of the natural compounds: azidation, halogenation, trifluoromethylation and electrochemical oxidation - will be discussed in this review.

Keywords: terpenes, C-H functionalization, azidation, oxidation, halogenation.