STUDIUL CINETICII OXIDĂRII UNOR ANTIBIOTICE DIN CLASA FLUORCHINOLONELOR ÎN SISTEMUL FQ-H2O2-UV

Tatiana ISAC-GUŢUL, Elena TUTOVAN Universitatea de Stat din Moldova

Аннотация

THE STUDY OF THE KINETICS OF SOME FLUORQUINOLONES  OXIDATION IN FQ-H2O2-UV SYSTEM

Fluorquinolones (FQ) are a class of antibiotics that manifest a broad spectrum of antibacterial activity. Due to their extensive usage, fluoroquinolones may enter the aquatic environment what constitutes a danger for the ecosystem and human health by causing the increase and spread of bacteria drug resistance. This is why it is very important to solve the problem of deep FQ oxidation by applying advanced oxidation processes (AOPs). It used UV, UV/H2O2, O3/UV, Fenton, photo-Fenton systems, in which free radicals are generated, the last one represent a cyclic process with regeneration of Fe2+ ions. The systems are the promising treatment options for wastewaters of pharmaceutical industry. In this paper was studied the kinetics of oxidation of four FQs – ofloxacin (OF), levofloxacin (LFX), ciprofloxacin (CPF) and moxifloxacin (MOX) under UV irradiation and by the UV-H2O2 system by the spectrophotometric method. Antibiotic concentrations varied from 12,5 to 30 mg/L. During the work „ ДРТ”-1000” lamp as a irradiation source was used.

Keywords: AOPs, photolysis, oxidation, fluoroquinolones.