ANTIMICROBIAL ACTIVITY OF SOME VINYL-TRIAZOLE DERIVATIVES
Galina LUPAȘCU, Svetlana GAVZER, Nicolae CRISTEA, Lucian LUPAȘCU, Eugenia STÎNGACI, Marina ZVEAGHINȚEVA, Serghei POGREBNOI, Fliur MACAEV, Institutul de Genetică, Fiziologie și Protecție a Plantelor, Institutul de Chimie, Universitatea de Stat din Moldova
Аннотация
Mycoses and bacterioses in agricultural crops are very devastating, bringing enormous economic damage through
direct crop losses and compromising it due to pathogen toxin pollution, which makes them toxic to humans and
animals. Chemical plant protection procedures often become ineffective due to the easy adaptation of causative agents
to pesticides, the reduction of the protective effect under the influence of unfavorable conditions, toxicity, ecological
consequences. Starting from this, the aim of the research consisted in the identification of new compounds with
antifungal (Fusarium avenaceum) and antibacterial (Erwinia amilovora, E. carotovora, Xanthomonas campestris)
activity in in vitro conditions for further utilization in plant protection measures. Based on the growth of fungal
colonies and minimum bactericidal concentration, it was found that vinyl-triazole derivatives EPS-869, EPS-877,
EPS-880, EPS-892, EPS-165 (0,00125; 0,0025; 0,005; 0, 01%) shows high antimicrobial activity, the phenomenon
being due in particular to the compound factor.
Keywords: vinyl-triazole derivatives, concentration, activity, fungus, bacteria.
