VIABILITY AND ANTIMICROBIAL ACTIVITY OF STREPTOMYCES STRAINS FROM NCNM AFTER LYOPHILIZATION

Oleg CHISELIŢA, Svetlana BURŢEVA, Maxim BÎRSA, Valentina BULIMAGA*, Anastasia VASILICIUC Institute of Microbiology and Biotechnology, Academy of Science of Moldova *State University of Moldova

Аннотация

The article deals with the aspects related to lyophilization of streptomycetes strains, preserved in the National Collection of Nonpathogenic Microorganisms (NCNM). Was determined that lyophilization do not significantly modify the antimicrobial activity of streptomycetes. Maximum viability of strains of genus Streptomyces (83,2-90,2%) is ensured after lyophilization at initial titer by 9-11 log10UFC ml-1 in protective medium (gelatin 2,5% + glucose 7,5%) by rehydration with distillate water. Keywords: Streptomyces, lyophilization, cryoprotectants, viability, antimicrobial activity.