IMUNOREACTIVITATEA ÎNCRUCIŞATĂ POTENŢIALĂ A GLOBULINELOR DE REZERVĂ DIN SEMINŢE

Ala CHERDIVARĂ Universitatea de Stat din Moldova

Abstract

POTENTIAL CROSS IMMUNOREACTIVITY OF SEED STORAGE GLOBULINS 

Seed storage 7S and 11S globulins of peanut and soybean as natural components of food can lead to the development of increased allergic sensitivity caused by the intensive formation of allergen-specific immunoglobulin E (IgE). The amino acid sequences of the seed storage globulins are conservative, therefore, in the sequences of many of them there are sites that are close similar of IgE epitopes of 7S and 11S globulins of peanuts and soybeans. 

In the present work, a quantitative assessment of the probability of the presence of IgE epitopes determining the established cross immunoreactivity of seed storage globulins of peanuts and soybeans, in the sequences of 7S and 11S seed storage globulins of other plants was carried out. 

Keywords: seed storage globulins, allergens, IgE epitopes, peanut, soybean.